May 19, 2022

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Two early symptoms of Parkinson's disease were discovered.  They are not clear

Two early symptoms of Parkinson’s disease were discovered. They are not clear


  1. Parkinson’s disease is a neurodegenerative condition in which nerve cells that control movement in the brain are destroyed

  2. Parkinson’s disease is a progressive disease – symptoms appear gradually and worsen slowly

  3. It is not known exactly what causes Parkinson’s disease. How to prevent Parkinson’s disease also remains a mystery. So far, no method has been found that can reverse its effects

  4. Parkinson’s disease is difficult to diagnose because there is no screening test for it, and symptoms vary from person to person and are not specific

  5. However, the researchers found two early symptoms that could lead to Parkinson’s disease in the future. This is hearing loss and epilepsy

  6. More information can be found on the Onet homepage

Parkinson’s disease doesn’t just affect movement. What happens to the patient?

Parkinson’s disease is a progressive disorder of the nervous system. In it, the brain cells that control movement (motor skills) deteriorate. Hence symptoms such as involuntary muscle contractions (tremors), muscle stiffness or slowed movement. In fact, Parkinson’s disease doesn’t just affect movement. Patients may also experience olfactory and sleep disturbances Constipationfatigue, pain (especially in the extremities) Dizzinessanxiety or depression.

The disease develops slowly over the years. Early symptoms can be mild and imperceptible, sometimes beginning with a barely noticeable tremor in one hand. It is not known exactly what causes Parkinson’s disease. Scientists believe it is a combination of genetic, environmental (such as head injury) and lifestyle factors.

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How to prevent Parkinson’s disease also remains a mystery. So far, no method has been found that can reverse its effects. Parkinson’s disease treatment is largely symptomatic. While it may be comforting to know that Parkinson’s disease is life-altering, it is not life-threatening on its own (although complications can be serious). Furthermore, as the Parkinson’s Fund points out, it is possible for Parkinson’s disease to have a good or excellent quality of life. The key is a diagnosis as early as possible and adherence to prescribed treatments. Unfortunately, Parkinson’s disease is difficult to diagnose because there is no screening test for it, and symptoms vary from person to person and are nonspecific. The discovery by scientists from Queen Mary University of London may help change the situation.

Two new early symptoms associated with Parkinson’s disease

Researchers have identified two early symptoms of Parkinson’s disease (a paper on this appeared in JAMA Neurology). Newly discovered features, along with other symptoms noted in the years prior to diagnosis, can help diagnose and treat the disease at an early stage. These symptoms include hearing impairment and epilepsy. How did scientists discover this path?


  1. What happens in the brain of a patient with Parkinson’s?

The team analyzed the medical records of more than 1 million people who lived in East London between 1990 and 2018 (the site was chosen because of its highly ethnically diverse population). They found that neither race nor socioeconomic status was associated with the risk of developing Parkinson’s disease. They also found that epilepsy was associated with an increased risk of developing the disease (this supports 2016 suggestions; case reports indicate that Parkinson’s disease and epilepsy can coexist).

Another finding of the study was hearing loss that occurred five years before the diagnosis of Parkinson’s disease. “This is an interesting observation because it was first seen with Parkinson’s disease,” notes Michigan Institute of Neurological Disorders neurologist Aaron L. Ellenbogen. “Further exploration is really important to understand if this is more than just an observation and whether there really is a hidden mechanism linking the two.”

New dependencies in known symptoms of Parkinson’s disease

The study authors agree that more research is needed on hearing loss and its relationship to Parkinson’s disease, but suggest that it is part of the impairment of sensory processing that occurs in Parkinson’s disease.

In addition to the new potential risk factors, the researchers also found dependencies in the already known symptoms of the disease. He found that the tremor appeared 10 years before the diagnosis of Parkinson’s disease. Memory problems, which were the most frequently reported non-motor symptom related to Parkinson’s disease, may have appeared five years before diagnosis.

The disease has also been linked to other comorbidities such as type 2 diabetes. “Parkinson’s disease, although considered by many to be a disorder of the brain, affects many systems throughout the body,” noted Dr. Ellenbogen. “It’s not just about the motor aspects, but also the digestive and urogenital systems, sleep, cognition. I think people often forget that.” The neurologist also asserts that “a symptom or risk factor for Parkinson’s disease certainly does not mean that the disease will occur.” However, the results of this study give hope to identify and treat a group of people at risk of developing Parkinson’s disease as soon as possible.

We encourage you to listen to the last episode of the RESET podcast. This time we dedicate it to the problems of the perineum – a part of the body like any other. And while it interests us all, it’s still a taboo topic that we’re often too shy to talk about. What do hormonal changes and normal births change? How not to hurt the pelvic floor muscles and how to take care of them? How do we talk about the problems of the perineum with our daughters? About this and many other aspects of the problem in a new episode of the podcast.

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