The scientists determined “the level of antibodies bound to a number of SARS-CoV-2 target antigens, the neutralizing antibody and the strength of antibody binding,” the institute writes on its website. The study was conducted on the basis of 830 samples collected from 390 patients, and 12 different tests were conducted on it.
They measured several types of antibodies, different target antigens for SARS-CoV-2, the binding strength of antibodies to antigens, and neutralizing antibodies to the coronavirus.
The results show that there is a clear pattern of sensitivity and time of detection of SARS-CoV-2 antibodies. This depends on the design of the assay, the target antigen test, the strength of antibody binding, and the severity of COVID-19 over the study period, the researchers note.
Protection more than 430 days after infection
The researchers reported that they were able to detect total antibodies more than 430 days after infection and “without a predictable end point”. They emphasized that they were most likely able to protect the affected person for a longer period of time. This also applies to antibodies that neutralize viruses.
This result shows that convalescent people are able to generate long-term immune memory in response to COVID-19 infection. This means that most people who become infected may return to the infection, but the course of the disease will be much less severe.
High sensitivity tests
Tests that determine the level of total antibodies that were used to conduct the experiment “showed high sensitivity and a long time to potential detection with increased antibody aspiration.”
They were fundamentally different from the tests commonly used todayThey target only specific antibodies that decrease in number over time after infection or vaccination.
These data could contribute to a more targeted use of antibody tests and the correct interpretation of SARS-CoV-2 antibody results in everyday diagnostic work. In addition, it could help determine the duration of potential immune protection against SARS-CoV-2, the researchers concluded.
Echo Richards embodies a personality that is a delightful contradiction: a humble musicaholic who never brags about her expansive knowledge of both classic and contemporary tunes. Infuriatingly modest, one would never know from a mere conversation how deeply entrenched she is in the world of music. This passion seamlessly translates into her problem-solving skills, with Echo often drawing inspiration from melodies and rhythms. A voracious reader, she dives deep into literature, using stories to influence her own hardcore writing. Her spirited advocacy for alcohol isn’t about mere indulgence, but about celebrating life’s poignant moments.