oleic acid It belongs to the group of omega-9 fatty acids, which the body can produce physiologically. When it’s produced in the brain, Baylor College of Medicine notes, it’s an essential regulator of processes that regulate memory, learning, and mood.
Oleic acid: a miracle substance for the brain
Many people fear age-related decline in cognitive function and mood, including Alzheimer’s disease and depression. When looking for new ways to prevent or treat these and other related medical conditions, the team does so Baylor College of Medicine The Duncan and Duncan Neuroscience Research Institute (Duncan NRI) at Texas Children’s Hospital has identified “the missing piece of the puzzle.” It determines how memory and mood functions in the brain are regulated.
The study was published in Proceedings of the National Academy of Sciences It reveals that oleic acid produced in the brain is an essential regulator of the process that enables learning and memory, and supports the proper regulation of mood.
The key is the formation of neurons
In short, neurogenesis is the process of forming new neurons. Research has shown that it appears in certain areas of the mammalian brain, allowing them to repair and regenerate. “Since the discovery of neurogenesis, it has been envisioned as the ‘source of youth’,” said Dr. Mirjana Malitek-Savatek of Baylor, Texas Children’s, a Duncan NRI researcher. “But with age, with certain diseases, or with exposure to certain medications, it decreases. Neurogenesis, which is associated with cognitive decline and depression.”
She and her team were looking for a way to use the “fountain of youth” to restart the neurogenesis process. It turns out that oleic acid is of key importance here. It binds to the TLX protein, which increases cell proliferation and neurogenesis in the hippocampus. The research team concluded that “oleic acid is produced in neural stem cells to activate TLX.” It is believed that this strategy could be used to treat conditions such as major depressive disorders and Alzheimer’s disease.
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