December 5, 2022


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Have scientists found the 'Holy Grail' in biology?  It is a universal stem cell

Have scientists found the ‘Holy Grail’ in biology? It is a universal stem cell

Discoveries that could theoretically lead to such possibilities have already been awarded by the Nobel Committee.

Now the Chinese team has described in the prestigious journal Nature another breakthrough in manipulating the fate of cells. Researchers have identified a mixture of materials that make it possible to obtain them from more specialized cells – stem cellsIt is so universal that even an entire organism can arise from it.

Are you still learning or playing God?

Chinese researchers argue that … this is a method that, in a way, can replace fertilization.

Such an alternative to nature’s way of creating the origins of life is the holy grail of biology.
– says the professor. Sheng Ding.

Every living organism, with all its tissues and organs, develops from a single cell. After fertilization, this cell is called the zygote. As it begins to divide, it produces more and more specialized cells, which later form all parts of the body. However, when this happens, the cells gradually lose their comprehensiveness and no longer restore it.

After 20 years of understanding these mechanisms and testing thousands of materials, researchers have found three compounds that transform relatively easily-obtained pluripotent stem cells (in this case, mice) into more comprehensive mature cells.
The above zygote belongs to the whole cells.

They are so versatile that they can develop into embryonic and placental cells.

universal stem cell

Scientists confirmed the result genetic researchThese cells were then allowed to grow when injected into the early mouse fetus. The obtained cells also functioned as fully grown cells in this assay. The combination of materials developed by the researchers also means that subsequent generations of cells have also retained their full nature.

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This is important because it will allow for example to conduct a variety of research related to the beginning of life, incl. How the successive cells and structures that give rise to organs are formed.

In theory, in the distant future, it may even become possible to create new life or speed up the evolution of species, say scientists.

Of course, as they note, they will be born controversy, incl. of an ethical nature. Even today, there are discussions about the use of existing technologies. For example, consideration has been given to extending the time period in which a human fetus can be tested in the laboratory beyond the acceptable 14 days, the researchers note.

They claim that they are fully aware of the consequences of their research, but they assert that the scientist’s role is primarily to make new discoveries now, and that future generations, who have more knowledge and understanding, will be able to make the right decisions.

Source:, PAP