A covert team of government agents committed to the elimination of vampires dispatch a mysterious young woman named Saya, who in the guise of a schoolgirl, must uncover the origin of the demonic plague, eliminate the ghastly beasts and stop their reign of terror before time runs out. She is the last remaining original.

Painstakingly animated by the masters of Japan’s Production I.G. studios ("Dead Leaves", "Ghost in the Shell", "Kai Doh Maru", "Neon Genesis Evangelion", "Kill Bill"), "Blood: The Last Vampire" is the first fully digital work of animation ever produced.

Conceived in cooperation with Mamoru Oshii (Director, "Ghost in the Shell", "Patlabor – The Movie", "Patlabor 2"), and Directed by Hiroyuki Kitakubo ("Jojo’s Bizarre Adventure", "Black Magic M-66"), the film features character designs by charismatic illustrator Katsuya Terada ("Mirai Ninja", "Zeiram"), dynamic digital sound mixed in Hollywood and the voice talents of Youki Kodoh ("Snow Falling on Cedars") as Saya.

The film opened in mid-November of 2000 at Cine Saison Shibuya and several other major cities throughout Japan. Blood also played a limited theatrical run in the U.S. and was one of the first- ever features to be streamed over the Internet the day of its release on DVD.